Imitation vs Natural Vanilla Extract

[whisks]

After reading about taste comparisons between the two, I went out and bought a bottle of the imitation. I’m sold! I use it in all my baked goods, now, but still use the good stuff in things that aren’t baked.

[Casey.A]

Out of curiosity, what is considered high heat? Is 300F considered to high? I assume 350F is. And what about length of time? One person had wrote that pancakes are cooked quickly so the high heat doesn't really affect the flavor of pure vanilla extract. How does vanilla bean paste or vanilla bean seeds fare in the oven under "high heat"? Is the flavor there lost as well?