RE: Right hand/left hand: My DW (we've been married for 39 years) is a lefty. There were numerous things she had to learn to do using right-handed items growing up. I still remember one of the things she acquired very early in our marriage was left-handed shears for her sewing. So much more comfortable and easy to use.
Edited to fix a typo. It's too late for me to be at the keyboard.