Keep us posted! I'm fascinated by alternative garums/koji ferments, so would love to hear how the beef turns out.
From what I've read about koji, you lose somewhere in the ball park of 50% of enzyme activity as soon as the manufacturer dries the koji and throws the product in the fridge. Accounting for weight loss through drying, I imagine if you go 1:1 for beef to koji ratio, there shouldn't be too much of an issue. I went a little higher compared to other recipes in my ferment just in case; I think your only issue would be that the final product might be a little sweeter from extra rice, but hopefully that gets fermented off by the salt-tolerant yeasts. I'd say you can add fresh miso to let them grab a foothold, otherwise it might take longer for them to inoculate from the air.
Disclaimer: I'm not a food safety expert.
How much salt are you using? If you're above 18% total weight, I don't think you need to worry about hitting the danger zones because the salt content would keep everything safe. For what it's worth, I think most garums and sauces are made just a bit north of room temperature - going 140 F might trash the koji enzymes (and any fermenting microbes) if you're going for several months, vs. if you were doing sous vide and only needing the enzymes for +3 days. I wish I had a copy of the Noma Guide to look through and see what they have to say about garum, I only have their posted articles to work off of.
There's a Japanese paper (literally, most of it is in Japanese I found an English translation!) that says in the abstract that their pork meat sauce (shishibishio) was fermented at 30 C (86 F) for 6 months. So I think you should be fine from a food safety standpoint if you wanted to keep things closer to room temperature without needing temperature and humidity controls. You could raise to 37 - 40 C to give the enzyme and bacteria a speed boost, but that's about it. The only thing I can think of is to keep exposing the ferment to oxygen when you mix to prevent C. botulinum from forming, but your salt should mostly take care of that.
sorry about that, couldn't find a translation
I hope that helps!