I've been thinking about this one. Are you coming into town for particular nights or are you asking as a general question. I only ask because I keep thinking of great places and then I know that at some of them you will get a different reception on a Friday/Saturday night than you would during the week. The places that came to mind are: 3 Doors Down in se Ptld, Fife in ne Ptld (although I haven't been there yet), and Pho Bistro in nw Portland. I'll try to tailor my thoughts more if you expound on what you're looking for. Oh. Also, there's a great "underground" called Ripe. They are doing Wednesday night soup, bread, and beer in their coffee ship. There is also live music and the people are great. Hope this helps, Neeley