I know this is an old thread, but I wanted to chime in with my similar experience. Last night I had one draft pint of Odell IPA with a burger and fries. I was in agony all night and most of today. The headache is still dully present. Like the original poster, my headaches are caused usually by beer, but also rarely by wine. It is a small percentage of the beer and wine that I drink that causes this. If it were more common I would probably stop drinking altogether, but it's quite rare. I would LOVE to be able to avoid these headaches. One notable thing is that I've never found any pain medicine that has any effect on these headaches. I am also fairly certain mine are not migraines, because, for example, they do not cause any visual effects. As far as placement, my headaches are usually behind my eyes, sometimes more one side than the other, but last night's was centered / behind both. If anyone can point me to any resources about this I'd appreciate it, and I am thinking that I'll mention it to my doctor next time I have a physical. Like chappie I have never had any problem with chocolate, cheese, or cured meats. The Wikipedia page for tyramine mentions research finding that certain neurotransmitters and neuromodulators including tyramine and others are found in elevated levels during migraines and cluster headaches, but that doesn't mean the chemical was ingested.