With the right accent, the right clothes and the right posture, I can see Meryl Streep pulling it off. I'm not a big Streep fan, but I actually can see it working. The biggest danger as I see it (and the reason I'm NOT a Streep fan), is the possibility of it becoming more of a satire than a depiction. I may be in the minority, but a lot of Meryl Streep's work seems overdone and takes me completely out of the narrative being illustrated. But I'm crabby and inclined to bitch, so, it's probably just me.